Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STM1620Putative oxidase; Similar to E. coli L-lactate dehydrogenase (AAC76629.1); Blastp hit to AAC76629.1 (396 aa), 38% identity in aa 212 - 384, 33% identity in aa 22 - 175. (400 aa)    
Predicted Functional Partners:
STM1621
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74140.1); Blastp hit to AAC74140.1 (191 aa), 33% identity in aa 1 - 190; Belongs to the UPF0312 family.
  
    0.786
poxB
Pyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors, cytoplasmic in absence of cofactors; Similar to E. coli pyruvate oxidase (AAC73958.1); Blastp hit to AAC73958.1 (572 aa), 94% identity in aa 1 - 572; Belongs to the TPP enzyme family.
  
 
 0.726
ydiJ
Similar to E. coli putative oxidase (AAC74757.1); Blastp hit to AAC74757.1 (1018 aa), 88% identity in aa 1 - 1017.
  
 0.695
STM1556
Putative Na+/H+ antiporter; Similar to E. coli transport of dicarboxylates (AAC73722.1); Blastp hit to AAC73722.1 (461 aa), 23% identity in aa 36 - 414.
  
  
 0.677
STM2768
Putative transposase; Similar to E. coli orf, hypothetical protein (AAC75149.1); Blastp hit to AAC75149.1 (102 aa), 85% identity in aa 4 - 102.
  
 
 0.595
nifJ
Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174.
  
  
 0.546
phnW
2-aminoethylphosphonate transport; Involved in phosphonate degradation.
  
 0.515
STM2739
Fels-2 prophage protein; Similar to int protein in phage 186; similar to E. coli prophage DLP12 integrase (AAC73638.1); Blastp hit to AAC73638.1 (387 aa), 41% identity in aa 302 - 363, 24% identity in aa 66 - 280, 35% identity in aa 19 - 50.
   
  
 0.508
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.489
lldP
LctP transporter; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force (By similarity).
  
 0.484
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.