Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ydaAPutative universal stress protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family. (315 aa)    
Predicted Functional Partners:
ybdQ
Putative universal stress protein UspA and related nucleotide-binding protein; Similar to E. coli orf, hypothetical protein (AAC73708.1); Blastp hit to AAC73708.1 (142 aa), 89% identity in aa 1 - 142.
   
  
 0.974
ynaF
Similar to E. coli putative filament protein (AAC74458.1); Blastp hit to AAC74458.1 (168 aa), 90% identity in aa 25 - 168.
   
  
 0.974
uspA
Universal stress protein A; Required for resistance to DNA-damaging agents.
  
  
 0.961
yecG
Putative universal stress protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
   
  
 0.936
fnr
Transcriptional regulator; Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metabolism. When the terminal electron acceptor, O(2), is no longer available, it represses the synthesis of enzymes involved in aerobic respiration and increases the synthesis of enzymes required for anaerobic respiration (By similarity).
  
 0.935
ogt
O-6-alkylguanine-DNA; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
    0.864
uspB
Universal stress protein B; Involved in stationary-phase resistance to ethanol; similar to E. coli orf, hypothetical protein (AAC76519.1); Blastp hit to AAC76519.1 (111 aa), 95% identity in aa 1 - 111.
  
  
 0.782
pspC
Phage shock protein; Regulatory gene; activates expression of psp operon with PspB; similar to E. coli phage shock protein: activates phage shock-protein expression (AAC74388.1); Blastp hit to AAC74388.1 (119 aa), 84% identity in aa 1 - 119.
  
     0.755
yfbV
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75355.1); Blastp hit to AAC75355.1 (151 aa), 95% identity in aa 1 - 151.
  
    0.736
metJ
Transcriptional repressor of all met genes but metF; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. It is also autoregulated (By similarity); Belongs to the MetJ family.
  
     0.724
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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