Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ynaIPutative integral membrane protein; Similar to E. coli orf, hypothetical protein (AAC74412.1); Blastp hit to AAC74412.1 (343 aa), 77% identity in aa 1 - 335. (343 aa)    
Predicted Functional Partners:
yedA
Similar to E. coli putative transmembrane subunit (AAC75025.1); Blastp hit to AAC75025.1 (306 aa), 89% identity in aa 1 - 298.
      
 0.851
ybiO
Similar to E. coli putative transport protein (AAC73895.1); Blastp hit to AAC73895.1 (786 aa), 85% identity in aa 46 - 786.
      
 0.801
yggT
Similar to E. coli putative resistance protein (AAC75989.1); Blastp hit to AAC75989.1 (188 aa), 90% identity in aa 1 - 188.
     
 0.734
mscL
Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.642
ymfB
Putative MutT-like protein; Similar to E. coli putative phosphohydrolase (AAC74218.1); Blastp hit to AAC74218.1 (153 aa), 84% identity in aa 1 - 152; Belongs to the Nudix hydrolase family. NudJ subfamily.
   
  
 0.551
gcvP
Glycine cleavage complex protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
    0.500
ynaJ
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74414.1); Blastp hit to AAC74414.1 (85 aa), 88% identity in aa 1 - 84.
     
 0.491
tyrS
Tyrosine tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
  
  
 0.459
yfhC
Putative cytosine/adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
     
 0.453
nhaA
NhaA family of transport protein, Na+/H antiporter, pH dependent; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
 
   
 0.421
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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