Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
STM1669Invasin-like protein; Homology to invasin C of Yersinia; similar to E. coli putative factor (AAC74304.1); Blastp hit to AAC74304.1 (417 aa), 30% identity in aa 38 - 403. (660 aa)    
Predicted Functional Partners:
STM1668
Putative outer membrane or exported protein.
  
  
 0.958
pagN
Homolog of sapA; Haemagglutinin that facilitates the adhesion to and invasion of epithelial mammalian cells. Utilizes heparinated proteoglycan as a receptor to successfully invade host cells.
   
  
 0.898
STM1670
Putative serine/threonine protein kinase.
  
  
 0.881
invA
Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
      
 0.858
fliC
Flagellar biosynthesis; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
    
 
 0.748
fimH
Minor fimbrial subunit; Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). A mannose-binding adhesin (By similarity). Belongs to the fimbrial protein family.
   
  
 0.727
STM1667
Similar to E. coli thiol peroxidase (AAC74406.1); Blastp hit to AAC74406.1 (168 aa), 30% identity in aa 45 - 159.
  
  
 0.722
fljB
Filament structural protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
    
 
 0.716
ompA
Putative membrane component hydrogenase; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.
  
 
 0.694
STM1674
Putative AraC family bacterial regulatory helix-turn-helix protein; Similar to E. coli orf, hypothetical protein (AAC77208.1); Blastp hit to AAC77208.1 (84 aa), 46% identity in aa 1 - 84.
   
    0.662
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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