Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ycjISimilar to E. coli putative carboxypeptidase (AAC74408.1); Blastp hit to AAC74408.1 (262 aa), 90% identity in aa 21 - 262. (242 aa)    
Predicted Functional Partners:
STM3605
Putative phage endolysin.
      
 0.769
nlpC
Lipoprotein; Similar to E. coli lipoprotein (AAC74778.1); Blastp hit to AAC74778.1 (154 aa), 86% identity in aa 1 - 154.
      
 0.719
ycjG
Similar to E. coli putative muconate cycloisomerase I (AAC74407.1); Blastp hit to AAC74407.1 (335 aa), 85% identity in aa 15 - 335.
  
 
 0.679
yiaH
Putative inner membrane protein; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.
  
     0.673
yccR
Putative DNA transformation protein; Similar to E. coli orf, hypothetical protein (AAC74045.1); Blastp hit to AAC74045.1 (209 aa), 75% identity in aa 1 - 199.
  
     0.639
ycgQ
Putative resistance protein MccF; Homologs of microcin C7; similar to E. coli orf, hypothetical protein (AAC74276.1); Blastp hit to AAC74276.1 (304 aa), 79% identity in aa 1 - 304.
 
 
 0.623
mppA
Periplasmic murein tripeptide transport protein; Also negative regulator of mulitple antibiotic resistance; similar to E. coli putative transport periplasmic protein (AAC74411.1); Blastp hit to AAC74411.1 (544 aa), 92% identity in aa 8 - 544.
  
  
 0.588
STM1849
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74904.1); Blastp hit to AAC74904.1 (879 aa), 90% identity in aa 1 - 879.
  
    0.584
hnr
Response regulator in protein turnover; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.
  
    0.556
nlpB
Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.539
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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