STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycjGSimilar to E. coli putative muconate cycloisomerase I (AAC74407.1); Blastp hit to AAC74407.1 (335 aa), 85% identity in aa 15 - 335. (321 aa)    
Predicted Functional Partners:
yjjY
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77355.1); Blastp hit to AAC77355.1 (46 aa), 97% identity in aa 1 - 46.
      
 0.899
ygeA
Putative aspartate racemase; Similar to E. coli putative resistance proteins (AAC75879.1); Blastp hit to AAC75879.1 (230 aa), 79% identity in aa 1 - 230; Belongs to the aspartate/glutamate racemases family.
      
 0.898
tyrR
Transcriptional regulatory protein TyrR; Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalani [...]
 
 
  
 0.794
ycjI
Similar to E. coli putative carboxypeptidase (AAC74408.1); Blastp hit to AAC74408.1 (262 aa), 90% identity in aa 21 - 262.
  
 
 0.639
tpx
Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
       0.548
pepD
Similar to E. coli aminoacyl-histidine dipeptidase (peptidase D) (AAC73341.1); Blastp hit to AAC73341.1 (485 aa), 92% identity in aa 1 - 485.
     
 0.540
yhgN
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76459.1); Blastp hit to AAC76459.1 (197 aa), 72% identity in aa 4 - 39.
      
 0.501
yajO
Putative oxidoreductase / K + channel protein; Similar to E. coli putative NAD(P)H-dependent xylose reductase (AAC73522.1); Blastp hit to AAC73522.1 (348 aa), 92% identity in aa 25 - 348.
   
  
 0.465
yjaD
Putative NTP pyrophosphohydrolases containing a Zn-finger; Probably nucleic-acid-binding; NADH pyrophosphatase. (SW:NUDC_SALTY).
      
 0.459
rfbI-2
CDP-6-deoxy-delta3,4-glucoseen reductase; LPS side chain defect; RFBI protein. (SW:RFBI_SALTY).
  
  
 0.458
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.