STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpxThiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (168 aa)    
Predicted Functional Partners:
lepB
Leader peptidase (signal peptidase I), serine protease; Signal peptidase I. (SW:LEP_SALTY); Belongs to the peptidase S26 family.
   
    0.724
yhbO
Putative intracellular proteinase; Similar to E. coli orf, hypothetical protein (AAC76187.1); Blastp hit to AAC76187.1 (186 aa), 94% identity in aa 15 - 186.
  
 
 0.708
sodB
Iron superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.707
STM0402
Similar to E. coli alkyl hydroperoxide reductase, C22 subunit; detoxification of hydroperoxides (AAC73706.1); Blastp hit to AAC73706.1 (187 aa), 36% identity in aa 1 - 186.
  
  
 0.672
sodA
Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.646
slyB
Outer membrane lipoprotein SLYB precursor. (SW:SLYB_SALTY).
   
  
 0.645
trxA
Thioredoxin 1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions; Belongs to the thioredoxin family.
  
 
 0.571
yobF
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74894.1); Blastp hit to AAC74894.1 (47 aa), 93% identity in aa 1 - 47.
   
    0.553
ycjG
Similar to E. coli putative muconate cycloisomerase I (AAC74407.1); Blastp hit to AAC74407.1 (335 aa), 85% identity in aa 15 - 335.
       0.548
pal
Tol protein required for outer membrane integrity; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
   
  
 0.543
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.