STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycjXSimilar to E. coli putative EC 2.1 enzymes (AAC74403.1); Blastp hit to AAC74403.1 (465 aa), 93% identity in aa 1 - 465. (467 aa)    
Predicted Functional Partners:
ycjF
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74404.1); Blastp hit to AAC74404.1 (353 aa), 88% identity in aa 1 - 353.
  
 0.999
pspD
Similar to E. coli phage shock protein (AAC74389.1); Blastp hit to AAC74389.1 (73 aa), 87% identity in aa 1 - 72.
  
  
 0.943
tyrR
Transcriptional regulatory protein TyrR; Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalani [...]
  
  
 0.903
pspB
Phage shock protein; Regulatory gene; activates expression of psp operon with PspC; similar to E. coli phage shock protein (AAC74387.1); Blastp hit to AAC74387.1 (74 aa), 89% identity in aa 1 - 74.
 
  
 0.852
pspC
Phage shock protein; Regulatory gene; activates expression of psp operon with PspB; similar to E. coli phage shock protein: activates phage shock-protein expression (AAC74388.1); Blastp hit to AAC74388.1 (119 aa), 84% identity in aa 1 - 119.
  
  
 0.834
yidE
Similar to E. coli putative transport protein (AAC76708.1); Blastp hit to AAC76708.1 (561 aa), 88% identity in aa 9 - 561.
      
 0.718
mepA
Penicillin-insensitive murein DD-endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family.
  
     0.711
pspA
Phage shock protein; Negative regulatory gene for the psp opreon; similar to E. coli phage shock protein, inner membrane protein (AAC74386.1); Blastp hit to AAC74386.1 (222 aa), 91% identity in aa 1 - 222.
  
  
 0.680
pspE
Similar to E. coli phage shock protein (AAC74390.1); Blastp hit to AAC74390.1 (104 aa), 66% identity in aa 1 - 103.
  
  
 0.595
pldB
Similar to E. coli lysophospholipase L(2) (AAC76828.1); Blastp hit to AAC76828.1 (340 aa), 81% identity in aa 1 - 336.
  
     0.550
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.