Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pspESimilar to E. coli phage shock protein (AAC74390.1); Blastp hit to AAC74390.1 (104 aa), 66% identity in aa 1 - 103. (104 aa)    
Predicted Functional Partners:
pspD
Similar to E. coli phage shock protein (AAC74389.1); Blastp hit to AAC74389.1 (73 aa), 87% identity in aa 1 - 72.
  
  
 0.961
pspB
Phage shock protein; Regulatory gene; activates expression of psp operon with PspC; similar to E. coli phage shock protein (AAC74387.1); Blastp hit to AAC74387.1 (74 aa), 89% identity in aa 1 - 74.
  
  
 0.947
pspA
Phage shock protein; Negative regulatory gene for the psp opreon; similar to E. coli phage shock protein, inner membrane protein (AAC74386.1); Blastp hit to AAC74386.1 (222 aa), 91% identity in aa 1 - 222.
  
  
 0.937
pspC
Phage shock protein; Regulatory gene; activates expression of psp operon with PspB; similar to E. coli phage shock protein: activates phage shock-protein expression (AAC74388.1); Blastp hit to AAC74388.1 (119 aa), 84% identity in aa 1 - 119.
  
  
 0.911
ycjX
Similar to E. coli putative EC 2.1 enzymes (AAC74403.1); Blastp hit to AAC74403.1 (465 aa), 93% identity in aa 1 - 465.
  
  
 0.816
glpE
Thiosulfate/cyanide sulfurtransferase; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
  
  
 0.776
pspF
Similar to E. coli psp operon transcriptional activator (AAC74385.1); Blastp hit to AAC74385.1 (330 aa), 86% identity in aa 6 - 330.
     
 0.710
ydeJ
Putative competence-damaged protein; Similar to E. coli orf, hypothetical protein (AAC74610.1); Blastp hit to AAC74610.1 (172 aa), 61% identity in aa 1 - 171; Belongs to the CinA family.
      
 0.643
ycjF
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74404.1); Blastp hit to AAC74404.1 (353 aa), 88% identity in aa 1 - 353.
  
  
 0.605
sapB
ABC superfamily peptide transport protein; Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides.
     
 0.505
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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