STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pspAPhage shock protein; Negative regulatory gene for the psp opreon; similar to E. coli phage shock protein, inner membrane protein (AAC74386.1); Blastp hit to AAC74386.1 (222 aa), 91% identity in aa 1 - 222. (222 aa)    
Predicted Functional Partners:
pspC
Phage shock protein; Regulatory gene; activates expression of psp operon with PspB; similar to E. coli phage shock protein: activates phage shock-protein expression (AAC74388.1); Blastp hit to AAC74388.1 (119 aa), 84% identity in aa 1 - 119.
 
 
 0.999
pspB
Phage shock protein; Regulatory gene; activates expression of psp operon with PspC; similar to E. coli phage shock protein (AAC74387.1); Blastp hit to AAC74387.1 (74 aa), 89% identity in aa 1 - 74.
 
 0.999
pspF
Similar to E. coli psp operon transcriptional activator (AAC74385.1); Blastp hit to AAC74385.1 (330 aa), 86% identity in aa 6 - 330.
 
 
 0.997
pspD
Similar to E. coli phage shock protein (AAC74389.1); Blastp hit to AAC74389.1 (73 aa), 87% identity in aa 1 - 72.
  
  
 0.988
yjfI
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77138.1); Blastp hit to AAC77138.1 (133 aa), 64% identity in aa 1 - 132.
  
  
 0.929
yjbO
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77020.1); Blastp hit to AAC77020.1 (150 aa), 82% identity in aa 71 - 150.
   
  
 0.896
pspE
Similar to E. coli phage shock protein (AAC74390.1); Blastp hit to AAC74390.1 (104 aa), 66% identity in aa 1 - 103.
  
  
 0.886
ycjF
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74404.1); Blastp hit to AAC74404.1 (353 aa), 88% identity in aa 1 - 353.
     
 0.795
rpoE
Sigma E (sigma 24) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase (RNAP) to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma-E controls the envelope stress response, responding to periplasmic protein stress, increased levels of periplasmic lipopolysaccharide (LPS) as well as acid stress, heat shock and oxidative stress; it controls protein processing in the extracytoplasmic compartment (By similarity).
   
  
 0.731
arcB
Sensory histidine kinase in two-component regulatory system with ArcA; Senses redox conditions; similar to E. coli aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA (AAC76242.1); Blastp hit to AAC76242.1 (776 aa), 93% identity in aa 1 - 776.
    
 
 0.720
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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