Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yciWPutative cytoplasmic protein; Similar to E. coli putative oxidoreductase (AAC74369.1); Blastp hit to AAC74369.1 (401 aa), 51% identity in aa 27 - 350. (326 aa)    
Predicted Functional Partners:
yfbK
Putative von Willebrand factor, vWF type A domain protein; Similar to E. coli orf, hypothetical protein (AAC75330.1); Blastp hit to AAC75330.1 (575 aa), 45% identity in aa 22 - 190.
      
 0.814
cysJ
Sulfite reductase, beta (flavoprotein) subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
   
  
 0.791
cysN
ATP-sulfurylase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
   
  
 0.790
cysI
NADPH dependent sulfite reductase, alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
   
  
 0.733
yqaA
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75736.1); Blastp hit to AAC75736.1 (142 aa), 90% identity in aa 1 - 141.
      
 0.724
yfbB
Putative enzyme; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
      
 0.723
ybfE
LexA regulated, putative SOS response; Similar to E. coli orf, hypothetical protein (AAC73779.1); Blastp hit to AAC73779.1 (120 aa), 90% identity in aa 24 - 120.
      
 0.722
yeaL
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74859.1); Blastp hit to AAC74859.1 (148 aa), 94% identity in aa 1 - 130.
      
 0.721
ybeU
Putative cytoplasmic protein; Similar to E. coli putative tRNA ligase (AAC73749.1); Blastp hit to AAC73749.1 (235 aa), 61% identity in aa 1 - 235.
      
 0.717
cysP
Thiosulfate transport protein; Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport (By similarity).
   
    0.708
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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