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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yciNPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74355.1); Blastp hit to AAC74355.1 (83 aa), 92% identity in aa 1 - 83. (83 aa)    
Predicted Functional Partners:
yafV
Similar to E. coli putative EC 3.5. amidase-type enzyme (AAC73323.1); Blastp hit to AAC73323.1 (256 aa), 82% identity in aa 3 - 255.
      
 0.896
smg
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76309.1); Blastp hit to AAC76309.1 (157 aa), 94% identity in aa 1 - 157; Belongs to the Smg family.
      
 0.893
yfeD
Putative negative regulator; Similar to E. coli orf, hypothetical protein (AAC75456.1); Blastp hit to AAC75456.1 (130 aa), 70% identity in aa 1 - 129.
      
 0.892
ppdB
Prepilin peptidase dependent protein B; Putative component in type IV pilin biogenesis; similar to E. coli prepilin peptidase dependent protein B (AAC75864.1); Blastp hit to AAC75864.1 (187 aa), 67% identity in aa 3 - 187.
      
 0.833
yegH
Similar to E. coli putative transport protein (AAC75124.1); Blastp hit to AAC75124.1 (549 aa), 90% identity in aa 23 - 549.
      
 0.767
yabI
Putative DedA family membrane protein; Similar to E. coli orf, hypothetical protein (AAC73176.1); Blastp hit to AAC73176.1 (254 aa), 89% identity in aa 1 - 253.
      
 0.761
yncC
Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74532.1); Blastp hit to AAC74532.1 (240 aa), 58% identity in aa 20 - 238.
      
 0.761
ucpA
Similar to E. coli putative oxidoreductase (AAC75479.1); Blastp hit to AAC75479.1 (285 aa), 92% identity in aa 23 - 285; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.717
glgS
rpoS dependent glycogen biosynthesis protein; Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.
      
 0.716
yoaE
Similar to E. coli putative transport protein (AAC74886.1); Blastp hit to AAC74886.1 (518 aa), 90% identity in aa 1 - 518.
      
 0.700
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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