Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yciAPutative Acyl-CoA hydrolase; Catalyzes the hydrolysis of the thioester bond in palmitoyl- CoA and malonyl-CoA. (133 aa)    
Predicted Functional Partners:
yciC
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74337.1); Blastp hit to AAC74337.1 (247 aa), 87% identity in aa 1 - 247.
 
  
 0.941
yciB
Putative intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
 
    0.862
ybgC
Putative esterase; Similar to E. coli orf, hypothetical protein (AAC73830.1); Blastp hit to AAC73830.1 (134 aa), 92% identity in aa 1 - 134.
  
  
 0.774
yciI
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74333.1); Blastp hit to AAC74333.1 (130 aa), 91% identity in aa 33 - 130.
 
    0.726
tesB
Similar to E. coli acyl-CoA thioesterase II (AAC73555.1); Blastp hit to AAC73555.1 (286 aa), 91% identity in aa 1 - 286.
   
  
 0.659
fabA
Beta-hydroxydecanoyl thioester dehydrase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
  
  
 0.576
tesA
Similar to E. coli acyl-CoA thioesterase I; also functions as protease I (AAC73596.1); Blastp hit to AAC73596.1 (208 aa), 89% identity in aa 2 - 205.
     
 0.569
yfcX
Putative dehydrogenase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.467
fadB
3-hydroxyacyl-coA dehydrogenase of 4-enzyme FadB protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 
 0.467
STM1733
Similar to E. coli putative ferredoxin (AAC73391.1); Blastp hit to AAC73391.1 (109 aa), 74% identity in aa 1 - 109.
       0.444
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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