| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cls | yciU | STM1739 | STM1740 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. | 0.715 |
| cueR | yciU | STM0499 | STM1740 | Putative heavy metal transcriptional repressor (MerR family); Regulates the transcription of the copA and cuiD (cueO) genes. Detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. | 0.403 |
| guaC | nrdH | STM0141 | STM2805 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Glutaredoxin-like protein; Electron transport system for the ribonucleotide reductase system NrdEF. | 0.487 |
| guaC | ybdO | STM0141 | STM0606 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73704.1); Blastp hit to AAC73704.1 (300 aa), 54% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family. | 0.459 |
| guaC | yciU | STM0141 | STM1740 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. | 0.824 |
| guaC | yeeF | STM0141 | STM2068 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Similar to E. coli putative amino acid/amine transport protein (AAC75075.1); Blastp hit to AAC75075.1 (454 aa), 99% identity in aa 1 - 454. | 0.766 |
| nrdH | guaC | STM2805 | STM0141 | Glutaredoxin-like protein; Electron transport system for the ribonucleotide reductase system NrdEF. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.487 |
| nrdH | yciU | STM2805 | STM1740 | Glutaredoxin-like protein; Electron transport system for the ribonucleotide reductase system NrdEF. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. | 0.697 |
| nrdH | yeeF | STM2805 | STM2068 | Glutaredoxin-like protein; Electron transport system for the ribonucleotide reductase system NrdEF. | Similar to E. coli putative amino acid/amine transport protein (AAC75075.1); Blastp hit to AAC75075.1 (454 aa), 99% identity in aa 1 - 454. | 0.663 |
| ybdO | guaC | STM0606 | STM0141 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73704.1); Blastp hit to AAC73704.1 (300 aa), 54% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.459 |
| ybdO | yciU | STM0606 | STM1740 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73704.1); Blastp hit to AAC73704.1 (300 aa), 54% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. | 0.716 |
| ybdO | yeeF | STM0606 | STM2068 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73704.1); Blastp hit to AAC73704.1 (300 aa), 54% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family. | Similar to E. coli putative amino acid/amine transport protein (AAC75075.1); Blastp hit to AAC75075.1 (454 aa), 99% identity in aa 1 - 454. | 0.697 |
| yciU | cls | STM1740 | STM1739 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.715 |
| yciU | cueR | STM1740 | STM0499 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. | Putative heavy metal transcriptional repressor (MerR family); Regulates the transcription of the copA and cuiD (cueO) genes. Detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations. | 0.403 |
| yciU | guaC | STM1740 | STM0141 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.824 |
| yciU | nrdH | STM1740 | STM2805 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. | Glutaredoxin-like protein; Electron transport system for the ribonucleotide reductase system NrdEF. | 0.697 |
| yciU | ybdO | STM1740 | STM0606 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73704.1); Blastp hit to AAC73704.1 (300 aa), 54% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family. | 0.716 |
| yciU | yeeF | STM1740 | STM2068 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. | Similar to E. coli putative amino acid/amine transport protein (AAC75075.1); Blastp hit to AAC75075.1 (454 aa), 99% identity in aa 1 - 454. | 0.895 |
| yciU | yehS | STM1740 | STM2157 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75185.1); Blastp hit to AAC75185.1 (156 aa), 90% identity in aa 1 - 155. | 0.891 |
| yciU | ynaJ | STM1740 | STM1662 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74414.1); Blastp hit to AAC74414.1 (85 aa), 88% identity in aa 1 - 84. | 0.897 |