STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yciUPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74330.1); Blastp hit to AAC74330.1 (135 aa), 92% identity in aa 27 - 135; Belongs to the UPF0263 family. (109 aa)    
Predicted Functional Partners:
ynaJ
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74414.1); Blastp hit to AAC74414.1 (85 aa), 88% identity in aa 1 - 84.
   
  
 0.898
yeeF
Similar to E. coli putative amino acid/amine transport protein (AAC75075.1); Blastp hit to AAC75075.1 (454 aa), 99% identity in aa 1 - 454.
      
 0.896
yehS
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75185.1); Blastp hit to AAC75185.1 (156 aa), 90% identity in aa 1 - 155.
   
  
 0.861
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
      
 0.768
cls
Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
  
    0.710
ybdO
Similar to E. coli putative transcriptional regulator LYSR-type (AAC73704.1); Blastp hit to AAC73704.1 (300 aa), 54% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family.
      
 0.693
nrdH
Glutaredoxin-like protein; Electron transport system for the ribonucleotide reductase system NrdEF.
      
 0.677
cueR
Putative heavy metal transcriptional repressor (MerR family); Regulates the transcription of the copA and cuiD (cueO) genes. Detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations.
   
  
 0.409
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.