Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
narXSensory histidine kinase in two component regulatory system with NarL; Senses nitrate/nitrite; regulates anaerobic respiration and fermentation; similar to E. coli nitrate/nitrate sensor, histidine protein kinase acts on NarL regulator (AAC74306.1); Blastp hit to AAC74306.1 (598 aa), 86% identity in aa 1 - 598. (598 aa)    
Predicted Functional Partners:
narL
Response regulator in two-component regulatory system with NarX (or NarQ); Regulates anaerobic respiration and fermentation (LuxR/UhpA family); similar to E. coli pleiotrophic regulation of anaerobic respiration: response regulator for nar, frd, dms and tor genes (AAC74305.1); Blastp hit to AAC74305.1 (216 aa), 96% identity in aa 1 - 216.
 
 0.999
narP
Response regulator in two-component regulatory system with NarQ (or NarX); Similar to E. coli nitrate/nitrite response regulator (sensor NarQ) (AAC75253.1); Blastp hit to AAC75253.1 (215 aa), 88% identity in aa 1 - 215.
 
 
 0.980
narK
Similar to E. coli nitrite extrusion protein (AAC74307.1); Blastp hit to AAC74307.1 (463 aa), 94% identity in aa 1 - 462.
 
  
 0.966
narG
Similar to E. coli nitrate reductase 1, alpha subunit (AAC74308.1); Blastp hit to AAC74308.1 (1247 aa), 95% identity in aa 1 - 1247; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
  
 0.928
torS
Histidine kinase; Regulates tor operon; similar to E. coli sensor protein torS (regulator TorR) (AAC74078.1); Blastp hit to AAC74078.1 (904 aa), 62% identity in aa 1 - 896.
     
 0.868
dcuS
Sensory histidine kinase in two-component retgulatory system with DcuR; Senses fumarate/C4-dicarboxylate; similar to E. coli putative 2-component sensor protein (AAC77086.1); Blastp hit to AAC77086.1 (543 aa), 81% identity in aa 1 - 542.
      
 0.860
narJ
Nitrate reductase 1, delta subunit; Chaperone required for molybdenum cofactor assembly in nitrate reductase 1; similar to E. coli nitrate reductase 1, delta subunit, assembly function (AAC74310.1); Blastp hit to AAC74310.1 (236 aa), 88% identity in aa 1 - 236.
 
  
 0.764
ssrB
Secretion system regulator: transcriptonal activator; Homologous with degU/uvrY/bvgA; SsrB (gi|2765824).
 
 
 0.746
fimZ
Fimbrial protein Z; Putative transcriptional regulator (LuxR/UhpA family); fimbriae Z protein. (SW:FIMZ_SALTY).
 
 
 
 0.743
narH
Similar to E. coli nitrate reductase 1, beta subunit (AAC74309.1); Blastp hit to AAC74309.1 (512 aa), 92% identity in aa 1 - 511.
  
  
 0.743
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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