STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dadXAlanine racemase 2; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. (356 aa)    
Predicted Functional Partners:
dadA
D-amino acid dehydrogenase subunit; Oxidative deamination of D-amino acids.
  
  
 0.999
murF
D-alanine:D-alanine-adding enzyme; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
   
 0.951
ddlB
D-alanine-D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.948
ddlA
D-alanine-D-alanine ligase A; Cell wall formation.
 
 
 0.943
alr
Biosynthetic alanine racemase 1; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis.
  
  
0.919
putA
Plasma membrane proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
 0.901
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
   
 0.838
yneH
Similar to E. coli putative glutaminase (AAC74597.1); Blastp hit to AAC74597.1 (308 aa), 91% identity in aa 1 - 308; Belongs to the glutaminase family.
     
 0.837
glnA
Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
     
 0.834
ilvE
Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine.
     
 0.830
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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