| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| STM1549 | yjeF | STM1549 | STM4356 | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC77205.1); Blastp hit to AAC77205.1 (131 aa), 82% identity in aa 1 - 129. | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | 0.463 |
| STM1549 | yjgF | STM1549 | STM4458 | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC77205.1); Blastp hit to AAC77205.1 (131 aa), 82% identity in aa 1 - 129. | Putative translation initiation inhibitor; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities and to avoid they are captured by anthranilate phosphoribosyltransferase (TrpD) to generate PRA, an intermediate in the alternative pyrimidine biosynthetic (APB) pathwa [...] | 0.826 |
| STM1549 | yoaB | STM1549 | STM1822 | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC77205.1); Blastp hit to AAC77205.1 (131 aa), 82% identity in aa 1 - 129. | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC74879.1); Blastp hit to AAC74879.1 (130 aa), 92% identity in aa 17 - 130. | 0.954 |
| dadA | yoaB | STM1803 | STM1822 | D-amino acid dehydrogenase subunit; Oxidative deamination of D-amino acids. | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC74879.1); Blastp hit to AAC74879.1 (130 aa), 92% identity in aa 17 - 130. | 0.472 |
| miaB | yoaB | STM0670 | STM1822 | Methylthiolation of isopentenylated A37 derivatives in rRNA; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC74879.1); Blastp hit to AAC74879.1 (130 aa), 92% identity in aa 17 - 130. | 0.467 |
| yeaZ | yoaA | STM1820 | STM1821 | Putative molecular chaperone; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). Neither binds polyphosphates nor a wide range of nucleotides on its own. Does n [...] | Putative DNA helicase; Similar to E. coli putative enzyme (AAC74878.1); Blastp hit to AAC74878.1 (636 aa), 95% identity in aa 1 - 635. | 0.692 |
| yeaZ | yoaB | STM1820 | STM1822 | Putative molecular chaperone; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). Neither binds polyphosphates nor a wide range of nucleotides on its own. Does n [...] | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC74879.1); Blastp hit to AAC74879.1 (130 aa), 92% identity in aa 17 - 130. | 0.476 |
| yieH | yoaB | STM3852 | STM1822 | Similar to E. coli putative phosphatase (AAC76738.1); Blastp hit to AAC76738.1 (221 aa), 81% identity in aa 1 - 220. | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC74879.1); Blastp hit to AAC74879.1 (130 aa), 92% identity in aa 17 - 130. | 0.475 |
| yieH | yrfG | STM3852 | STM3496 | Similar to E. coli putative phosphatase (AAC76738.1); Blastp hit to AAC76738.1 (221 aa), 81% identity in aa 1 - 220. | Similar to E. coli putative phosphatase (AAC76424.1); Blastp hit to AAC76424.1 (237 aa), 85% identity in aa 16 - 237. | 0.899 |
| yjeF | STM1549 | STM4356 | STM1549 | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC77205.1); Blastp hit to AAC77205.1 (131 aa), 82% identity in aa 1 - 129. | 0.463 |
| yjeF | yjgF | STM4356 | STM4458 | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | Putative translation initiation inhibitor; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities and to avoid they are captured by anthranilate phosphoribosyltransferase (TrpD) to generate PRA, an intermediate in the alternative pyrimidine biosynthetic (APB) pathwa [...] | 0.463 |
| yjeF | ymfB | STM4356 | STM1235 | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | Putative MutT-like protein; Similar to E. coli putative phosphohydrolase (AAC74218.1); Blastp hit to AAC74218.1 (153 aa), 84% identity in aa 1 - 152; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.537 |
| yjeF | yoaB | STM4356 | STM1822 | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC74879.1); Blastp hit to AAC74879.1 (130 aa), 92% identity in aa 17 - 130. | 0.463 |
| yjgF | STM1549 | STM4458 | STM1549 | Putative translation initiation inhibitor; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities and to avoid they are captured by anthranilate phosphoribosyltransferase (TrpD) to generate PRA, an intermediate in the alternative pyrimidine biosynthetic (APB) pathwa [...] | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC77205.1); Blastp hit to AAC77205.1 (131 aa), 82% identity in aa 1 - 129. | 0.826 |
| yjgF | yjeF | STM4458 | STM4356 | Putative translation initiation inhibitor; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities and to avoid they are captured by anthranilate phosphoribosyltransferase (TrpD) to generate PRA, an intermediate in the alternative pyrimidine biosynthetic (APB) pathwa [...] | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | 0.463 |
| yjgF | yoaB | STM4458 | STM1822 | Putative translation initiation inhibitor; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities and to avoid they are captured by anthranilate phosphoribosyltransferase (TrpD) to generate PRA, an intermediate in the alternative pyrimidine biosynthetic (APB) pathwa [...] | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC74879.1); Blastp hit to AAC74879.1 (130 aa), 92% identity in aa 17 - 130. | 0.846 |
| ymfB | yjeF | STM1235 | STM4356 | Putative MutT-like protein; Similar to E. coli putative phosphohydrolase (AAC74218.1); Blastp hit to AAC74218.1 (153 aa), 84% identity in aa 1 - 152; Belongs to the Nudix hydrolase family. NudJ subfamily. | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | 0.537 |
| ymfB | yoaB | STM1235 | STM1822 | Putative MutT-like protein; Similar to E. coli putative phosphohydrolase (AAC74218.1); Blastp hit to AAC74218.1 (153 aa), 84% identity in aa 1 - 152; Belongs to the Nudix hydrolase family. NudJ subfamily. | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC74879.1); Blastp hit to AAC74879.1 (130 aa), 92% identity in aa 17 - 130. | 0.527 |
| yoaA | yeaZ | STM1821 | STM1820 | Putative DNA helicase; Similar to E. coli putative enzyme (AAC74878.1); Blastp hit to AAC74878.1 (636 aa), 95% identity in aa 1 - 635. | Putative molecular chaperone; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). Neither binds polyphosphates nor a wide range of nucleotides on its own. Does n [...] | 0.692 |
| yoaA | yoaB | STM1821 | STM1822 | Putative DNA helicase; Similar to E. coli putative enzyme (AAC74878.1); Blastp hit to AAC74878.1 (636 aa), 95% identity in aa 1 - 635. | Putative translation initiation inhibitor; Similar to E. coli orf, hypothetical protein (AAC74879.1); Blastp hit to AAC74879.1 (130 aa), 92% identity in aa 17 - 130. | 0.542 |
