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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rrmA23S rRNA m1G745 methyltransferase; Similar to E. coli putative enzyme (AAC74892.1); Blastp hit to AAC74892.1 (269 aa), 80% identity in aa 1 - 268. (269 aa)    
Predicted Functional Partners:
yneJ
Similar to E. coli putative transcriptional regulator LYSR-type (AAC74599.1); Blastp hit to AAC74599.1 (293 aa), 84% identity in aa 1 - 283; Belongs to the LysR transcriptional regulatory family.
   
  
 0.832
ftsI-2
Putative penicillin-binding protein-3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
 
  
 0.798
stiA
Putative fimbrial subunit; Similar to E. coli major type 1 subunit fimbrin (pilin) (AAC77270.1); Blastp hit to AAC77270.1 (182 aa), 37% identity in aa 1 - 181.
   
  
 0.763
gutM
Putative glucitol (srl) operon regulatory protein; Similar to E. coli glucitol operon activator (AAC75748.1); Blastp hit to AAC75748.1 (119 aa), 83% identity in aa 1 - 119.
      
 0.698
yciH
Putative translation initiation factor SUI1; Protein YCIH. (SW:YCIH_SALTY); Belongs to the SUI1 family.
   
  
 0.690
sthE
Putative major fimbrial subunit.
   
  
 0.659
cspC
Cold shock protein; Multicopy suppresses mukB mutants, putative regulator; cold shock-like protein CSPC. (SW:CSPC_SALTY).
    
 0.647
aegA
Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC75521.1); Blastp hit to AAC75521.1 (659 aa), 85% identity in aa 1 - 651.
  
  
 0.584
tolA
Similar to E. coli membrane spanning protein, required for outer membrane integrity (AAC73833.1); Blastp hit to AAC73833.1 (421 aa), 70% identity in aa 1 - 420.
      
 0.579
dapE
N-succinyl-diaminopimelate deacylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. Can also hydrolyze all N-terminal Asp dipeptides except Asp-Pro. Asp-Ser is the best substrate, followed by Asp-Gly, Asp-Leu, and Asp- Cys; Belongs to the peptidase M20A family. DapE subfamily.
  
    0.558
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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