Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kdgRPutative IclR family transcriptional repressor; Similar to E. coli putative regulator (AAC74897.1); Blastp hit to AAC74897.1 (263 aa), 96% identity in aa 1 - 263. (263 aa)    
Predicted Functional Partners:
STM2668
Putative cytoplasmic protein.
      0.876
sun
Putative rRNA methylase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
      
 0.860
kdgT
2-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity); Belongs to the KdgT transporter family.
   
  
 0.728
kdgK
Similar to E. coli ketodeoxygluconokinase (AAC76551.1); Blastp hit to AAC76551.1 (382 aa), 92% identity in aa 74 - 381.
 
  
 0.712
eda
Multifunctional; similar to E. coli 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase (AAC74920.1); Blastp hit to AAC74920.1 (213 aa), 97% identity in aa 1 - 212; oxaloacetate decarboxylase.
  
  
 0.565
STM1843
Similar to E. coli putative transport protein (AAC74898.1); Blastp hit to AAC74898.1 (494 aa), 90% identity in aa 38 - 494.
     
 0.549
ybgJ
Similar to E. coli putative carboxylase (AAC73805.1); Blastp hit to AAC73805.1 (218 aa), 86% identity in aa 1 - 218.
  
    0.527
ybgK
Similar to E. coli putative carboxylase (AAC73806.1); Blastp hit to AAC73806.1 (310 aa), 84% identity in aa 1 - 310.
  
    0.514
crp
Catabolite activator protein (CAP); A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding to regulate transcription. It can act as an activator, repressor, coactivator or corepressor. Induces a severe bend in DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP. Plays a major role in carbon catabolite repression (CCR) (By similarity).
   
  
 0.446
yebO
Putative periplasmic or exported protein; Similar to E. coli orf, hypothetical protein (AAC74895.1); Blastp hit to AAC74895.1 (95 aa), 73% identity in aa 1 - 95.
   
  
 0.434
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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