Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STM1870recE-like protein; Similar to E. coli exonuclease VIII, ds DNA exonuclease, 5' --> 3' specific (AAC74432.1); Blastp hit to AAC74432.1 (866 aa), 52% identity in aa 406 - 521, 20% identity in aa 543 - 585. (164 aa)    
Predicted Functional Partners:
STM0281
Putative cytoplasmic protein.
      
 0.947
STM2005
Putative endoprotease.
   
  
 0.947
yiiG
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76878.1); Blastp hit to AAC76878.1 (351 aa), 67% identity in aa 15 - 351.
      
 0.947
STM2486
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75528.1); Blastp hit to AAC75528.1 (287 aa), 92% identity in aa 1 - 286.
     
 0.927
STM1791
Putative hydrogenase-1 protein; Similar to E. coli nickel incorporation into hydrogenase-1 proteins (AAC74062.1); Blastp hit to AAC74062.1 (285 aa), 75% identity in aa 1 - 279.
      
 0.896
STM1871
Similar to E. coli prophage e14 integrase (AAC74224.1); Blastp hit to AAC74224.1 (375 aa), 39% identity in aa 78 - 366; Belongs to the 'phage' integrase family.
  
    0.741
napB
Periplasmic small subunit nitrate reductase of cytochrome C550; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.
      
 0.724
recC
Exonuclease V, subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzy [...]
  
 
 0.576
STM1869A
Hypothetical protein.
  
    0.554
hisB
Imidazole glycerol-phosphate dehydratase; Bifunctional; histidine biosynthesis bifunctional protein HISB [includes:histidinol-phosphatase ]. (SW:HIS7_SALTY); In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
      
 0.548
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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