Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ptrBProtease II; Similar to E. coli protease II (AAC74915.1); Blastp hit to AAC74915.1 (686 aa), 89% identity in aa 1 - 680. (683 aa)    
Predicted Functional Partners:
ptr
Protease III; Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.
      
 0.726
yggB
Putative membrane protein; Involved in stability of MscS mechanosensitive channel; similar to E. coli putative transport protein (AAC75961.1); Blastp hit to AAC75961.1 (286 aa), 91% identity in aa 1 - 285.
   
  
 0.647
tldD
Similar to E. coli suppresses inhibitory activity of CsrA (AAC76276.1); Blastp hit to AAC76276.1 (481 aa), 94% identity in aa 1 - 481.
      
 0.579
yhbO
Putative intracellular proteinase; Similar to E. coli orf, hypothetical protein (AAC76187.1); Blastp hit to AAC76187.1 (186 aa), 94% identity in aa 15 - 186.
   
  
 0.518
yebE
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74916.1); Blastp hit to AAC74916.1 (219 aa), 86% identity in aa 1 - 217.
  
    0.486
rlpA
A minor lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides; Belongs to the RlpA family.
  
  
 0.427
hslV
Peptidase component of the HslUV protease; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. Belongs to the peptidase T1B family. HslV subfamily.
     
 0.422
dcp
Dipeptidyl carboxypeptidase II; Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides.
  
  
 0.413
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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