Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
znuAABC superfamily high affinity Zn transport protein; Binding protein; similar to E. coli putative adhesin (AAC74927.1); Blastp hit to AAC74927.1 (328 aa), 85% identity in aa 1 - 328. (333 aa)    
Predicted Functional Partners:
znuC
ABC superfamily high affinity Zn transport protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system (Probable). Seems to be important for the virulence.
 
 
 0.999
znuB
ABC superfamily high affinity Zn transport protein; ATP-binding protein; similar to E. coli orf, hypothetical protein (AAC74929.1); Blastp hit to AAC74929.1 (261 aa), 96% identity in aa 1 - 261.
 
 
 0.999
STM1263
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75039.1); Blastp hit to AAC75039.1 (216 aa), 71% identity in aa 3 - 216.
 
  
 0.983
yebA
Putative peptidase; Similar to E. coli orf, hypothetical protein (AAC74926.1); Blastp hit to AAC74926.1 (419 aa), 91% identity in aa 1 - 419.
 
  
 0.974
ygiE
Putative divalent heavy-metal cations transporter; Mediates zinc uptake. May also transport other divalent cations such as copper and cadmium ions (By similarity); Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
     
 0.901
sitD
Fur regulated Salmonella iron transporter; SitD (gi|5231097).
 
  
 0.864
zntA
P-type ATPase family; Pb/Cd/Zn/Hg transporting ATPase; similar to E. coli zinc-transporting ATPase (AAC76494.1); Blastp hit to AAC76494.1 (732 aa), 84% identity in aa 1 - 731.
   
  
 0.858
sitC
Fur regulated Salmonella iron transporter; SitC (gi|5231096).
 
  
 0.844
sitB
Fur regulated Salmonella iron transporter; SitB (gi|5231095).
 
  
 0.818
zntB
Putative Zn transport protein; Mediates efflux of zinc ions.
      
 0.763
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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