| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| btuD | cbiO | STM1342 | STM2020 | Vitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. | 0.923 |
| btuD | cboQ | STM1342 | STM2021 | Vitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiQ family. | 0.900 |
| btuD | modF | STM1342 | STM0778 | Vitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | Putative ABC superfamily (atp_bind), molybdenum transporter; Similar to E. coli ATP-binding component of molybdate transport system (AAC73847.1); Blastp hit to AAC73847.1 (490 aa), 31% identity in aa 1 - 211. | 0.900 |
| btuD | proW | STM1342 | STM2810 | Vitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | Glycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.900 |
| btuD | yjgQ | STM1342 | STM4480 | Vitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | Putative permease; Similar to E. coli orf, hypothetical protein (AAC77219.1); Blastp hit to AAC77219.1 (361 aa), 97% identity in aa 2 - 361. | 0.900 |
| btuD | znuC | STM1342 | STM1892 | Vitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | ABC superfamily high affinity Zn transport protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system (Probable). Seems to be important for the virulence. | 0.909 |
| cbiO | btuD | STM2020 | STM1342 | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. | Vitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | 0.923 |
| cbiO | cboQ | STM2020 | STM2021 | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiQ family. | 0.999 |
| cbiO | modF | STM2020 | STM0778 | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. | Putative ABC superfamily (atp_bind), molybdenum transporter; Similar to E. coli ATP-binding component of molybdate transport system (AAC73847.1); Blastp hit to AAC73847.1 (490 aa), 31% identity in aa 1 - 211. | 0.900 |
| cbiO | proW | STM2020 | STM2810 | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. | Glycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.900 |
| cbiO | yjgQ | STM2020 | STM4480 | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. | Putative permease; Similar to E. coli orf, hypothetical protein (AAC77219.1); Blastp hit to AAC77219.1 (361 aa), 97% identity in aa 2 - 361. | 0.900 |
| cbiO | znuC | STM2020 | STM1892 | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. | ABC superfamily high affinity Zn transport protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system (Probable). Seems to be important for the virulence. | 0.906 |
| cboQ | btuD | STM2021 | STM1342 | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiQ family. | Vitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | 0.900 |
| cboQ | cbiO | STM2021 | STM2020 | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiQ family. | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. | 0.999 |
| cboQ | modF | STM2021 | STM0778 | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiQ family. | Putative ABC superfamily (atp_bind), molybdenum transporter; Similar to E. coli ATP-binding component of molybdate transport system (AAC73847.1); Blastp hit to AAC73847.1 (490 aa), 31% identity in aa 1 - 211. | 0.900 |
| cboQ | proW | STM2021 | STM2810 | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiQ family. | Glycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.900 |
| cboQ | yjgQ | STM2021 | STM4480 | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiQ family. | Putative permease; Similar to E. coli orf, hypothetical protein (AAC77219.1); Blastp hit to AAC77219.1 (361 aa), 97% identity in aa 2 - 361. | 0.900 |
| cboQ | znuC | STM2021 | STM1892 | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiQ family. | ABC superfamily high affinity Zn transport protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system (Probable). Seems to be important for the virulence. | 0.921 |
| modF | btuD | STM0778 | STM1342 | Putative ABC superfamily (atp_bind), molybdenum transporter; Similar to E. coli ATP-binding component of molybdate transport system (AAC73847.1); Blastp hit to AAC73847.1 (490 aa), 31% identity in aa 1 - 211. | Vitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | 0.900 |
| modF | cbiO | STM0778 | STM2020 | Putative ABC superfamily (atp_bind), molybdenum transporter; Similar to E. coli ATP-binding component of molybdate transport system (AAC73847.1); Blastp hit to AAC73847.1 (490 aa), 31% identity in aa 1 - 211. | Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. | 0.900 |