STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yedEPutative membrane component of transport system; Hypothetical 44.2 Kda protein in amyA-fliE intergenic region. (SW:YEDE_SALTY). (421 aa)    
Predicted Functional Partners:
yedF
Putative transcriptional regulator; Hypothetical 8.6 Kda protein in amyA-fliE intergenic region (ORF 9). (SW:YEDF_ECOLI); Belongs to the sulfur carrier protein TusA family.
 
  
 0.999
selD
Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.
 
  
 0.731
selB
Similar to E. coli selenocysteinyl-tRNA-specific translation factor (AAC76614.1); Blastp hit to AAC76614.1 (614 aa), 85% identity in aa 1 - 614.
 
   
 0.715
selA
Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family.
 
  
 0.681
bax
Gene transcribed divergently from malS; Similar to E. coli putative ATP-binding protein (AAC76594.1); Blastp hit to AAC76594.1 (274 aa), 89% identity in aa 1 - 274.
  
     0.674
ychN
Putative ACR protein; Involved in intracellular sulfur reduction; similar to E. coli orf, hypothetical protein (AAC74303.1); Blastp hit to AAC74303.1 (117 aa), 92% identity in aa 1 - 117.
 
    0.598
yhhP
Small ubiquitous protein required for normal growth; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthes [...]
  
  
 0.578
yedD
Putative outer membrane lipoprotein; Hypothetical 15.5 Kda protein in amyA-fliE intergenic region. (SW:YEDD_SALTY).
  
    0.547
dmsC
Similar to E. coli anaerobic dimethyl sulfoxide reductase subunit C (AAC73982.1); Blastp hit to AAC73982.1 (287 aa), 89% identity in aa 1 - 287.
  
     0.442
STM1496
Similar to E. coli putative DMSO reductase anchor subunit (AAC74662.1); Blastp hit to AAC74662.1 (284 aa), 76% identity in aa 1 - 284.
  
     0.434
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.