STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yedFPutative transcriptional regulator; Hypothetical 8.6 Kda protein in amyA-fliE intergenic region (ORF 9). (SW:YEDF_ECOLI); Belongs to the sulfur carrier protein TusA family. (77 aa)    
Predicted Functional Partners:
yedE
Putative membrane component of transport system; Hypothetical 44.2 Kda protein in amyA-fliE intergenic region. (SW:YEDE_SALTY).
 
  
 0.999
ydiY
Putative salt-induced outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC74792.1); Blastp hit to AAC74792.1 (252 aa), 88% identity in aa 1 - 252.
      
 0.767
ychN
Putative ACR protein; Involved in intracellular sulfur reduction; similar to E. coli orf, hypothetical protein (AAC74303.1); Blastp hit to AAC74303.1 (117 aa), 92% identity in aa 1 - 117.
 
  
 0.756
ynaJ
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74414.1); Blastp hit to AAC74414.1 (85 aa), 88% identity in aa 1 - 84.
     
 0.718
nifS
Putative aminotransferase class-V; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate; Belongs to the class-V pyridoxal-phosphate-dependent [...]
   
 
 0.711
ydhK
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74717.1); Blastp hit to AAC74717.1 (670 aa), 84% identity in aa 1 - 669.
      
 0.696
selB
Similar to E. coli selenocysteinyl-tRNA-specific translation factor (AAC76614.1); Blastp hit to AAC76614.1 (614 aa), 85% identity in aa 1 - 614.
 
   
 0.651
ycaO
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73991.1); Blastp hit to AAC73991.1 (589 aa), 93% identity in aa 4 - 589.
      
 0.650
ybbB
Putative ATPase; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain (Probable); Belongs to the SelU family.
 
   
 0.614
bax
Gene transcribed divergently from malS; Similar to E. coli putative ATP-binding protein (AAC76594.1); Blastp hit to AAC76594.1 (274 aa), 89% identity in aa 1 - 274.
  
     0.593
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.