Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
STM1988Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75023.1); Blastp hit to AAC75023.1 (60 aa), 83% identity in aa 1 - 59. (81 aa)    
Predicted Functional Partners:
rmf
Ribosome modulation factor (involved in dimerization of 70S ribosomes); During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes). May form immature 90S particles, which are converted to mature 100S ribosomes by the hibernation promoting factor Hpf.
   
    0.811
yedI
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75024.1); Blastp hit to AAC75024.1 (305 aa), 85% identity in aa 3 - 305.
       0.737
lepB
Leader peptidase (signal peptidase I), serine protease; Signal peptidase I. (SW:LEP_SALTY); Belongs to the peptidase S26 family.
   
    0.525
yfiA
Ribosome associated factor; Stabilizes ribosomes against dissociation; similar to E. coli putative yhbH sigma 54 modulator (AAC75646.1); Blastp hit to AAC75646.1 (113 aa), 91% identity in aa 1 - 112.
   
    0.501
yfcH
Similar to E. coli putative sugar nucleotide epimerase (AAC75364.1); Blastp hit to AAC75364.1 (297 aa), 86% identity in aa 1 - 297.
   
    0.500
dgcQ
Putative inner membrane protein; Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (By similarity). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria. Involved in the regulation of cellulose production (By similarity).
       0.497
yedA
Similar to E. coli putative transmembrane subunit (AAC75025.1); Blastp hit to AAC75025.1 (306 aa), 89% identity in aa 1 - 298.
       0.494
yobF
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74894.1); Blastp hit to AAC74894.1 (47 aa), 93% identity in aa 1 - 47.
   
    0.491
nlpD
Lipoprotein; Activator of the cell wall hydrolase AmiC. Required for septal murein cleavage and daughter cell separation during cell division (By similarity); Belongs to the E.coli NlpD/Haemophilus LppB family.
   
    0.463
cspC
Cold shock protein; Multicopy suppresses mukB mutants, putative regulator; cold shock-like protein CSPC. (SW:CSPC_SALTY).
   
    0.425
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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