Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yedIPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75024.1); Blastp hit to AAC75024.1 (305 aa), 85% identity in aa 3 - 305. (303 aa)    
Predicted Functional Partners:
tnpA_3
Transposase for insertion sequence element is200 (SW:T200_SALTY).
      
 0.897
tnpA_1
IS200 transposase; Involved in the transposition of the insertion sequence.
      
 0.895
yheS
Contains duplicated ATPase domain; similar to E. coli putative ATP-binding component of a transport system (AAC76377.1); Blastp hit to AAC76377.1 (637 aa), 93% identity in aa 1 - 631.
      
 0.858
glyS
Similar to E. coli glycine tRNA synthetase, beta subunit (AAC76583.1); Blastp hit to AAC76583.1 (689 aa), 92% identity in aa 1 - 689.
     
 0.858
STM1988
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75023.1); Blastp hit to AAC75023.1 (60 aa), 83% identity in aa 1 - 59.
       0.737
dgcQ
Putative inner membrane protein; Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (By similarity). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria. Involved in the regulation of cellulose production (By similarity).
 
    0.735
yfdZ
Similar to E. coli putative aminotransferase (AAC75438.1); Blastp hit to AAC75438.1 (412 aa), 95% identity in aa 1 - 412.
  
  
 0.729
nrdB
Ribonucleoside-diphosphate reductase 1, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis; Belongs to the ribonucleoside diphosphate reductase small chain family.
      
 0.718
nfo
Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
      
 0.650
dctA
DAACS family C4-dicarboxylic acids transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
      
 0.591
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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