Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STM1999Putative cytoplasmic protein. (53 aa)    
Predicted Functional Partners:
umuD
Error-prone repair: SOS-response transcriptional repressor; Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template.
  
  
 0.871
STM2230
Putative peptidase; Similar to E. coli SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC (AAC74267.1); Blastp hit to AAC74267.1 (139 aa), 38% identity in aa 22 - 139; Belongs to the peptidase S24 family.
      
 0.670
umuC
Error-prone repair protein; Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template.
  
    0.653
prfH
Similar to E. coli probable peptide chain release factor (AAC73340.1); Blastp hit to AAC73340.1 (166 aa), 82% identity in aa 2 - 163.
      
 0.617
dsbB
Putative disulfide oxidoreductase; Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by oxidizing the DsbA protein (By similarity); Belongs to the DsbB family.
      
 0.613
cspB
Putative cold-shock protein; Similar to E. coli cold shock-like protein (AAC74625.1); Blastp hit to AAC74625.1 (70 aa), 84% identity in aa 1 - 70.
      
 0.549
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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