STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pduFPropanediol utilization protein; May facilitate the diffusion of propanediol; Belongs to the MIP/aquaporin (TC 1.A.8) family. (264 aa)    
Predicted Functional Partners:
pocR
Propanediol utilization protein; Positive regulatory protein of pdu and cob operons.
     
 0.946
pduP
Propanediol utilization CoA-dependent propionaldehyde dehydrogenase; Similar to E. coli ethanolamine utilization; similar to acetaldehyde dehydrogenase (AAC75508.1); Blastp hit to AAC75508.1 (467 aa), 45% identity in aa 1 - 466.
   
 
 0.904
pduQ
Propanediol utilization propanol dehydrogenase; Similar to E. coli CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; pyruvate-formate-lyase deactivase (AAC74323.1); Blastp hit to AAC74323.1 (891 aa), 40% identity in aa 574 - 860, 35% identity in aa 456 - 556.
   
  
 0.898
pduC
Propanediol utilization dehydratase, large subunit; Part of the PduCDE complex that catalyzes the dehydration of 1,2-propanediol to propionaldehyde. Is required for S.typhimurium growth on 1,2-propanediol as the sole carbon and energy source.
  
  
 0.896
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
 
 0.893
pduA
Polyhedral bodies; propanediol utilization protein PDUA. (SW:PDUA_SALTY).
   
  
 0.891
pduO
Propanediol utilization B12 related protein; Belongs to the Cob(I)alamin adenosyltransferase family.
  
  
 0.883
pduD
Propanediol utilization dehydratase, medium subunit; Part of the PduCDE complex that catalyzes the dehydration of 1,2-propanediol to propionaldehyde. Is required for S.typhimurium growth on 1,2-propanediol as the sole carbon and energy source.
  
  
 0.862
pduK
Propanediol utilization protein; Polyhedral bodies; similar to E. coli detox protein (AAC75510.1); Blastp hit to AAC75510.1 (111 aa), 35% identity in aa 9 - 92.
   
  
 0.812
pduM
Propanediol utilization protein.
     
 0.810
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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