Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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pduLPropanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. Is also able to catalyze the reverse reaction. To a lesser extent, also displays phosphate acetyltransferase activity. Belongs to the PduL family. (210 aa)    
Predicted Functional Partners:
pduP
Propanediol utilization CoA-dependent propionaldehyde dehydrogenase; Similar to E. coli ethanolamine utilization; similar to acetaldehyde dehydrogenase (AAC75508.1); Blastp hit to AAC75508.1 (467 aa), 45% identity in aa 1 - 466.
 
 
 0.999
pduW
Probable propionate kinase. (SW:PDUW_SALTY); Belongs to the acetokinase family. PduW subfamily.
 
 0.999
tdcD
Propionate kinase; Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP. It can also use acetyl phosphate as phosphate group acceptor; Belongs to the acetokinase family. TdcD subfamily.
  
 0.999
pduK
Propanediol utilization protein; Polyhedral bodies; similar to E. coli detox protein (AAC75510.1); Blastp hit to AAC75510.1 (111 aa), 35% identity in aa 9 - 92.
 
  
 0.993
pduO
Propanediol utilization B12 related protein; Belongs to the Cob(I)alamin adenosyltransferase family.
 
  
 0.993
ackA
Acetate kinase A; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Has broad substrate specificity and can also utilize GTP, UTP and CTP. Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate; Belongs to the acetokinase family.
  
 0.993
pduQ
Propanediol utilization propanol dehydrogenase; Similar to E. coli CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; pyruvate-formate-lyase deactivase (AAC74323.1); Blastp hit to AAC74323.1 (891 aa), 40% identity in aa 574 - 860, 35% identity in aa 456 - 556.
  
  
 0.992
pduN
Propanediol utilization protein; Polyhedral bodies; similar to E. coli detox protein (AAC75509.1); Blastp hit to AAC75509.1 (95 aa), 43% identity in aa 1 - 83.
 
  
 0.990
pduD
Propanediol utilization dehydratase, medium subunit; Part of the PduCDE complex that catalyzes the dehydration of 1,2-propanediol to propionaldehyde. Is required for S.typhimurium growth on 1,2-propanediol as the sole carbon and energy source.
 
  
 0.987
pduJ
Propanediol utilization protein; Polyhedral bodies; similar to E. coli detox protein (AAC75510.1); Blastp hit to AAC75510.1 (111 aa), 64% identity in aa 17 - 101.
 
  
 0.987
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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