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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dacDDD-carboxypeptidase; Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Belongs to the peptidase S11 family. (390 aa)    
Predicted Functional Partners:
yfeW
Similar to E. coli putative beta-lactamase (AAC75483.1); Blastp hit to AAC75483.1 (463 aa), 72% identity in aa 30 - 461; Belongs to the peptidase S12 family. YfeW subfamily.
     
 0.958
dacB
Similar to E. coli D-alanyl-D-alanine carboxypeptidase, fraction B; penicillin-binding protein 4 (AAC76214.1); Blastp hit to AAC76214.1 (477 aa), 93% identity in aa 1 - 477.
     
 0.950
mrcA
Similar to E. coli peptidoglycan synthetase; penicillin-binding protein 1A (AAC76421.1); Blastp hit to AAC76421.1 (858 aa), 92% identity in aa 1 - 858.
   
 
 0.932
dacA
Similar to E. coli D-alanyl-D-alanine carboxypeptidase, fraction A; penicillin-binding protein 5 (AAC73733.1); Blastp hit to AAC73733.1 (403 aa), 95% identity in aa 1 - 403; Belongs to the peptidase S11 family.
  
  
0.908
dacC
Similar to E. coli D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein 6 (AAC73926.1); Blastp hit to AAC73926.1 (400 aa), 92% identity in aa 1 - 400; Belongs to the peptidase S11 family.
  
  
0.908
ampH
Penicillin- binding protein; Similar to E. coli putative enzyme (AAC73479.1); Blastp hit to AAC73479.1 (385 aa), 91% identity in aa 10 - 385.
      
 0.897
ftsI
Division specific transpeptidase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
  
 
 0.866
mrcB
Transpeptidase of penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
   
  
 0.847
mrdA-2
Putative penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
 0.847
mtgA
Peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
   
 
 0.836
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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