STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfbPUndecaprenol-phosphate galactosephosphotransferase, and; Is responsible for transferring galactose-1-phosphate to the lipid precursor undecaprenol phosphate in the first steps of O- polysaccharide biosynthesis; Belongs to the bacterial sugar transferase family. (476 aa)    
Predicted Functional Partners:
rfbM
Mannose-1-phosphate guanylyltransferase; Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS group B O antigen; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  
 0.997
rfbN
LPS side chain defect: putative rhamnosyltransferase RFBN. (SW:RFBN_SALTY).
  
 0.995
rfbK
Phosphomannomutase; Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS group B O antigen; Belongs to the phosphohexose mutase family.
  
  
 0.989
wzc
Putative tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium (By similarity). Belongs to the etk/wzc family.
 
  
 0.989
rfbU
Mannosyl transferase; LPS side chain defect; RFBU protein. (SW:RFBU_SALTY).
 
  
 0.988
rfaL
O-antigen ligase; Adds the O-antigen on the glucose(II) group of LPS.
  
  
 0.986
rfbH
CDP-6deoxy-D-xylo-4-hexulose-3-dehydrase; LPS side chain defect; lipopolysaccharide biosynthesis protein RFBH. (SW:RFBH_SALTY); Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.981
gmd
GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
  
 0.971
wza
Putative polysaccharide export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium.
 
  
 0.970
rfbX
Putative O-antigen transferase; May be involved in the translocation process of the nascent O-polysaccharide molecules and/or its ligation to lipid A core units.
  
  
 0.949
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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