Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rfbKPhosphomannomutase; Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS group B O antigen; Belongs to the phosphohexose mutase family. (477 aa)    
Predicted Functional Partners:
rfbM
Mannose-1-phosphate guanylyltransferase; Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS group B O antigen; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
 0.999
rfbP
Undecaprenol-phosphate galactosephosphotransferase, and; Is responsible for transferring galactose-1-phosphate to the lipid precursor undecaprenol phosphate in the first steps of O- polysaccharide biosynthesis; Belongs to the bacterial sugar transferase family.
  
  
 0.990
cpsG
Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family.
    
 0.989
rfbN
LPS side chain defect: putative rhamnosyltransferase RFBN. (SW:RFBN_SALTY).
  
  
 0.987
manC
Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid.
  
 0.978
manA
Mannose-6-phosphate isomerase; Involved in the conversion of glucose to GDP-L-fucose, which can be converted to L-fucose, a capsular polysaccharide; Belongs to the mannose-6-phosphate isomerase type 1 family.
 
 
 0.962
rfbU
Mannosyl transferase; LPS side chain defect; RFBU protein. (SW:RFBU_SALTY).
  
  
 0.936
manY
Mannose-specific enzyme IIC; Sugar Specific PTS family; similar to E. coli PTS enzyme IIC, mannose-specific (AAC74888.1); Blastp hit to AAC74888.1 (266 aa), 94% identity in aa 1 - 266.
     
 0.921
manZ
Mannose-specific enzyme IID; Sugar Specific PTS family; similar to E. coli PTS enzyme IID, mannose-specific (AAC74889.1); Blastp hit to AAC74889.1 (286 aa), 92% identity in aa 1 - 285.
    
 0.921
manX
Mannose-specific enzyme IIAB; Sugar Specific PTS family; similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 95% identity in aa 1 - 323.
    
 0.919
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.