STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wcaJPutative UDP-glucose lipid carrier transferase; In colanic acid gene cluster; similar to E. coli putative colanic acid biosynthsis UDP-glucose lipid carrier transferase (AAC75108.1); Blastp hit to AAC75108.1 (464 aa), 89% identity in aa 1 - 464; glucose-1-phosphate transferase. (464 aa)    
Predicted Functional Partners:
wzc
Putative tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium (By similarity). Belongs to the etk/wzc family.
 
  
 0.988
wza
Putative polysaccharide export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium.
 
  
 0.983
wzb
Putative protein-tyrosine-phosphatase; Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis. Probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact-dependent growth inhibition (CDI).
  
  
 0.947
wzxC
Putative export protein; In colanic acid gene cluster; similar to E. coli probable export protein (AAC75107.1); Blastp hit to AAC75107.1 (492 aa), 85% identity in aa 1 - 492.
 
  
 0.925
wcaK
Putative galactokinase; In colanic acid gene cluster; similar to E. coli putative galactokinase. (AAC75106.1); Blastp hit to AAC75106.1 (426 aa), 67% identity in aa 1 - 426.
 
  
 0.882
gmd
GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
  
 0.869
manC
Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid.
 
  
 0.868
wcaA
Putative glycosyl transferase; In colanic acid gene cluster; similar to E. coli putative regulator (AAC75120.1); Blastp hit to AAC75120.1 (279 aa), 91% identity in aa 3 - 279.
 
  
 0.832
wcaL
Putative glycosyl transferase; In colanic acid gene cluster; putative colanic acid biosynthesis glycosyl transferase WCAL. (SW:WCAL_SALTY).
 
  
 0.825
cpsG
Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family.
  
  
 0.795
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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