Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
cpsGPhosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family. (456 aa)    
Predicted Functional Partners:
manC
Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid.
 
 0.999
rfbM
Mannose-1-phosphate guanylyltransferase; Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS group B O antigen; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 0.997
manA
Mannose-6-phosphate isomerase; Involved in the conversion of glucose to GDP-L-fucose, which can be converted to L-fucose, a capsular polysaccharide; Belongs to the mannose-6-phosphate isomerase type 1 family.
  
 
 0.990
rfbK
Phosphomannomutase; Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS group B O antigen; Belongs to the phosphohexose mutase family.
    
 0.989
gmd
GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
  
 0.952
galF
Putative glucose-1-phosphate uridylyltransferase, non-catalytic subunit; May play a role in stationary phase survival; Belongs to the UDPGP type 2 family.
  
 0.924
rfbC
dTDP-4,deoxyrhamnose 3,5 epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
   
 
 0.915
manX
Mannose-specific enzyme IIAB; Sugar Specific PTS family; similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 95% identity in aa 1 - 323.
    
 0.909
STM0577
Putative transport protein, PTS system; Similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 26% identity in aa 5 - 126.
     
  0.900
manY
Mannose-specific enzyme IIC; Sugar Specific PTS family; similar to E. coli PTS enzyme IIC, mannose-specific (AAC74888.1); Blastp hit to AAC74888.1 (266 aa), 94% identity in aa 1 - 266.
     
  0.900
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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