node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gmd | manC | STM2109 | STM2105 | GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | 0.997 |
gmd | wcaA | STM2109 | STM2115 | GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | Putative glycosyl transferase; In colanic acid gene cluster; similar to E. coli putative regulator (AAC75120.1); Blastp hit to AAC75120.1 (279 aa), 91% identity in aa 3 - 279. | 0.928 |
gmd | wcaB | STM2109 | STM2114 | GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | Putative acyl transferase; In colanic acid gene cluster; similar to E. coli putative transferase (AAC75119.1); Blastp hit to AAC75119.1 (162 aa), 91% identity in aa 1 - 160; Belongs to the transferase hexapeptide repeat family. | 0.841 |
gmd | wcaE | STM2109 | STM2111 | GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | Putative transferase; In colanic acid gene cluster; similar to E. coli putative colanic acid biosynthesis glycosyl transferase (AAC75116.1); Blastp hit to AAC75116.1 (248 aa), 71% identity in aa 1 - 248. | 0.944 |
gmd | wcaG | STM2109 | STM2108 | GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | Bifunctional GDP fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. | 0.999 |
gmd | wcaJ | STM2109 | STM2103 | GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | Putative UDP-glucose lipid carrier transferase; In colanic acid gene cluster; similar to E. coli putative colanic acid biosynthsis UDP-glucose lipid carrier transferase (AAC75108.1); Blastp hit to AAC75108.1 (464 aa), 89% identity in aa 1 - 464; glucose-1-phosphate transferase. | 0.869 |
gmd | wza | STM2109 | STM2118 | GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | Putative polysaccharide export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. | 0.878 |
gmd | wzb | STM2109 | STM2117 | GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | Putative protein-tyrosine-phosphatase; Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis. Probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact-dependent growth inhibition (CDI). | 0.731 |
gmd | wzc | STM2109 | STM2116 | GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | Putative tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium (By similarity). Belongs to the etk/wzc family. | 0.947 |
gmd | wzxC | STM2109 | STM2102 | GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | Putative export protein; In colanic acid gene cluster; similar to E. coli probable export protein (AAC75107.1); Blastp hit to AAC75107.1 (492 aa), 85% identity in aa 1 - 492. | 0.672 |
manC | gmd | STM2105 | STM2109 | Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | 0.997 |
manC | wcaA | STM2105 | STM2115 | Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Putative glycosyl transferase; In colanic acid gene cluster; similar to E. coli putative regulator (AAC75120.1); Blastp hit to AAC75120.1 (279 aa), 91% identity in aa 3 - 279. | 0.684 |
manC | wcaB | STM2105 | STM2114 | Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Putative acyl transferase; In colanic acid gene cluster; similar to E. coli putative transferase (AAC75119.1); Blastp hit to AAC75119.1 (162 aa), 91% identity in aa 1 - 160; Belongs to the transferase hexapeptide repeat family. | 0.595 |
manC | wcaE | STM2105 | STM2111 | Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Putative transferase; In colanic acid gene cluster; similar to E. coli putative colanic acid biosynthesis glycosyl transferase (AAC75116.1); Blastp hit to AAC75116.1 (248 aa), 71% identity in aa 1 - 248. | 0.639 |
manC | wcaG | STM2105 | STM2108 | Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Bifunctional GDP fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. | 0.921 |
manC | wcaJ | STM2105 | STM2103 | Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Putative UDP-glucose lipid carrier transferase; In colanic acid gene cluster; similar to E. coli putative colanic acid biosynthsis UDP-glucose lipid carrier transferase (AAC75108.1); Blastp hit to AAC75108.1 (464 aa), 89% identity in aa 1 - 464; glucose-1-phosphate transferase. | 0.868 |
manC | wza | STM2105 | STM2118 | Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Putative polysaccharide export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. | 0.811 |
manC | wzb | STM2105 | STM2117 | Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Putative protein-tyrosine-phosphatase; Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis. Probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact-dependent growth inhibition (CDI). | 0.766 |
manC | wzc | STM2105 | STM2116 | Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Putative tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium (By similarity). Belongs to the etk/wzc family. | 0.812 |
manC | wzxC | STM2105 | STM2102 | Mannose-1-phosphate; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Putative export protein; In colanic acid gene cluster; similar to E. coli probable export protein (AAC75107.1); Blastp hit to AAC75107.1 (492 aa), 85% identity in aa 1 - 492. | 0.577 |