STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdtAPutative HlyD family secretion protein; Similar to E. coli putative membrane protein (AAC75135.1); Blastp hit to AAC75135.1 (464 aa), 82% identity in aa 50 - 464; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (413 aa)    
Predicted Functional Partners:
yegN
Putative outer membrane receptor; Similar to E. coli orf, hypothetical protein (AAC75136.1); Blastp hit to AAC75136.1 (1040 aa), 91% identity in aa 1 - 1040; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
 
 0.999
yegO
Putative resistance protein; Efflux transporter; outer membrane; similar to E. coli orf, hypothetical protein (AAC75137.1); Blastp hit to AAC75137.1 (1025 aa), 91% identity in aa 1 - 1025; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
 
 0.999
acrD
RND family aminoglycoside/multidrug efflux pump; Similar to E. coli sensitivity to acriflavine, integral membrane protein, possible efflux pump (AAC75523.1); Blastp hit to AAC75523.1 (1037 aa), 94% identity in aa 1 - 1037.
 
 0.986
yegB
Similar to E. coli putative transport protein (AAC75138.1); Blastp hit to AAC75138.1 (471 aa), 85% identity in aa 1 - 469.
  
  
 0.971
baeS
Sensory kinase in two-component regulatoyr system wtih BaeR; Similar to E. coli sensor protein (for BaeR) (AAC75139.1); Blastp hit to AAC75139.1 (467 aa), 88% identity in aa 1 - 467.
  
  
 0.969
baeR
OmpR family; similar to E. coli transcriptional response regulatory protein (sensor BaeS) (AAC75140.1); Blastp hit to AAC75140.1 (240 aa), 96% identity in aa 1 - 240.
  
  
 0.963
ybjZ
Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.962
acrF
RND family multidrug transport protein; Similar to E. coli integral transmembrane protein; acridine resistance (AAC76298.1); Blastp hit to AAC76298.1 (1034 aa), 22% identity in aa 1 - 506; acriflavin resistance protein F.
 
 0.955
tolC
Outer membrane channel; Specific tolerance to colicin E1; segregation of daughter chromosomes; role in organic solvent tolerance; similar to E. coli outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (AAC76071.1); Blastp hit to AAC76071.1 (495 aa), 89% identity in aa 1 - 495.
  
 0.954
spy
Similar to E. coli periplasmic protein related to spheroblast formation (AAC74813.1); Blastp hit to AAC74813.1 (161 aa), 89% identity in aa 1 - 161.
   
  
 0.940
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.