Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
yegQPutative protease; Similar to E. coli orf, hypothetical protein (AAC75142.1); Blastp hit to AAC75142.1 (453 aa), 96% identity in aa 1 - 453. (453 aa)    
Predicted Functional Partners:
STM2135
Putative inner membrane protein.
  
  
 0.967
yhbV
Putative protease; Similar to E. coli orf, hypothetical protein (AAC76193.1); Blastp hit to AAC76193.1 (298 aa), 91% identity in aa 1 - 298.
 
 
 0.967
STM3261
Similar to E. coli galactitol-1-phosphate dehydrogenase (AAC75152.1); Blastp hit to AAC75152.1 (346 aa), 68% identity in aa 1 - 344.
   
  
 0.854
STM3262
Transcriptional regulator of sugar metabolism; Similar to E. coli split galactitol utilization operon repressor, interrupted (AAC75148.1); Blastp hit to AAC75148.1 (148 aa), 77% identity in aa 1 - 148.
      
 0.854
nuoC
NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
   0.796
yegS
Putative diacylglycerol kinase catalytic domain containing protein; In vitro does not phosphorylate diacylglycerol, sphingosine, N,N-dimethylsphingosine; threo-dihydrosphingosine, erythro- dihydrosphingosine, C2 ceramide, C6 ceramide, phosphatidylinositol or dimethylsphingosine. The potential in vivo substrate is unknown.
     
 0.778
yhcM
Putative ATPase; Reduces the stability of FtsZ polymers in the presence of ATP.
      
 0.710
yceA
Putative enzyme related to sulfur transferases; Similar to E. coli orf, hypothetical protein (AAC74139.1); Blastp hit to AAC74139.1 (350 aa), 88% identity in aa 1 - 350; Belongs to the UPF0176 family.
  
  
 0.697
baeS
Sensory kinase in two-component regulatoyr system wtih BaeR; Similar to E. coli sensor protein (for BaeR) (AAC75139.1); Blastp hit to AAC75139.1 (467 aa), 88% identity in aa 1 - 467.
 
    0.692
yhbT
Putative lipid carrier protein; Similar to E. coli orf, hypothetical protein (AAC76191.1); Blastp hit to AAC76191.1 (174 aa), 90% identity in aa 1 - 174.
 
  
 0.572
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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