Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pbpGD-alanyl-D-alanine endopeptidase; Penicillin-binding protein 7 and penicillin-binding protein 8; similar to E. coli penicillin-binding protein 7 (AAC75195.1); Blastp hit to AAC75195.1 (313 aa), 92% identity in aa 4 - 313; Belongs to the peptidase S11 family. (315 aa)    
Predicted Functional Partners:
yfeL
Putative membrane carboxypeptidase; Penicillin-binding protein; hypothetical 20.5 Kda protein in pdxK-cysM intergenic region. (SW:YFEL_SALTY).
   
  
 0.775
yebA
Putative peptidase; Similar to E. coli orf, hypothetical protein (AAC74926.1); Blastp hit to AAC74926.1 (419 aa), 91% identity in aa 1 - 419.
  
  
 0.739
yfeW
Similar to E. coli putative beta-lactamase (AAC75483.1); Blastp hit to AAC75483.1 (463 aa), 72% identity in aa 30 - 461; Belongs to the peptidase S12 family. YfeW subfamily.
      
 0.731
yohC
Putative transport protein; Similar to E. coli orf, hypothetical protein (AAC75196.1); Blastp hit to AAC75196.1 (203 aa), 91% identity in aa 9 - 203.
     
 0.713
ydhO
Putative cell wall-associated hydrolase; Similar to E. coli putative lipoprotein (AAC74727.1); Blastp hit to AAC74727.1 (271 aa), 72% identity in aa 1 - 271.
 
   
 0.637
ftsI-2
Putative penicillin-binding protein-3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
 
  
 0.617
ampD
N-acetyl-anhydromuramyl-L-alanine amidase; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
      
 0.599
ftsI
Division specific transpeptidase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
 
  
 0.577
mrdA-2
Putative penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
  
 0.566
spr
Putative lipoprotein; Suppresses thermosensitivity of prc mutants at low osmolality; similar to E. coli putative lipoprotein (AAC75236.1); Blastp hit to AAC75236.1 (188 aa), 92% identity in aa 1 - 188.
 
   
 0.492
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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