Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yohCPutative transport protein; Similar to E. coli orf, hypothetical protein (AAC75196.1); Blastp hit to AAC75196.1 (203 aa), 91% identity in aa 9 - 203. (195 aa)    
Predicted Functional Partners:
rsd
Regulator of sigma D; Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
  
    0.770
yjcB
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77030.1); Blastp hit to AAC77030.1 (116 aa), 83% identity in aa 24 - 116.
      
 0.769
alaE
Putative inner membrane protein; Exports L-alanine; Belongs to the AlaE exporter family.
      
 0.720
pbpG
D-alanyl-D-alanine endopeptidase; Penicillin-binding protein 7 and penicillin-binding protein 8; similar to E. coli penicillin-binding protein 7 (AAC75195.1); Blastp hit to AAC75195.1 (313 aa), 92% identity in aa 4 - 313; Belongs to the peptidase S11 family.
     
 0.713
yqiB
Putative cytoplasmic protein; Similar to E. coli putative enzyme (AAC76069.1); Blastp hit to AAC76069.1 (140 aa), 95% identity in aa 1 - 140.
  
     0.656
ycgB
Similar to E. coli putative sporulation protein (AAC74272.1); Blastp hit to AAC74272.1 (510 aa), 96% identity in aa 1 - 510.
   
  
 0.624
ygaM
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75719.1); Blastp hit to AAC75719.1 (113 aa), 86% identity in aa 1 - 112.
  
    0.588
yohD
Putative DedA family, membrane protein; Similar to E. coli orf, hypothetical protein (AAC75197.1); Blastp hit to AAC75197.1 (204 aa), 81% identity in aa 13 - 197.
  
    0.557
yicF
Putative DNA ligase; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
  
     0.519
STM0718
Putative cytoplasmic protein.
      
 0.512
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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