Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yohFSimilar to E. coli putative oxidoreductase (AAC75198.1); Blastp hit to AAC75198.1 (253 aa), 80% identity in aa 1 - 251. (253 aa)    
Predicted Functional Partners:
yjgB
Putative alcohol dehydrogenase; Similar to E. coli putative oxidoreductase (AAC77226.1); Blastp hit to AAC77226.1 (353 aa), 91% identity in aa 15 - 353.
  
 
 0.749
nuoC
NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
    
 
 0.679
yohG
Putative outer membrane efflux protein; Similar to E. coli putative channel/filament proteins (AAC75199.1); Blastp hit to AAC75199.1 (398 aa), 85% identity in aa 1 - 396.
       0.619
ybdR
Similar to E. coli putative oxidoreductase (AAC73709.1); Blastp hit to AAC73709.1 (412 aa), 91% identity in aa 1 - 412.
 
  
 0.520
ppx
Exopolyphosphatase; Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain.
   
  
 0.520
ygaU
Putative LysM domain protein; Similar to E. coli orf, hypothetical protein (AAC75712.1); Blastp hit to AAC75712.1 (149 aa), 93% identity in aa 1 - 149.
   
  
 0.519
gppA
Guanosine pentaphosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
      
 0.519
blc
Outer membrane lipoprotein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.
   
  
 0.518
ldcC
Similar to E. coli lysine decarboxylase 2, constitutive (AAC73297.1); Blastp hit to AAC73297.1 (713 aa), 91% identity in aa 1 - 712.
      
 0.512
fbaB
3-oxoacyl-[acyl-carrier-protein] synthase I; Similar to E. coli orf, hypothetical protein (AAC75158.1); Blastp hit to AAC75158.1 (374 aa), 96% identity in aa 25 - 374.
   
    0.495
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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