STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yeiGPutative esterase; Serine hydrolase involved in the detoxification of formaldehyde. (285 aa)    
Predicted Functional Partners:
STM1627
Similar to E. coli alcohol dehydrogenase class III; formaldehyde dehydrogenase, glutathione-dependent (AAC73459.1); Blastp hit to AAC73459.1 (369 aa), 80% identity in aa 1 - 369; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.999
fdhF
Formate dehydrogenase; Similar to E. coli selenopolypeptide subunit of formate dehydrogenase H (AAD13462.1); Blastp hit to AAD13462.1 (715 aa), 97% identity in aa 1 - 714; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
  0.908
fdoI
Similar to E. coli formate dehydrogenase, cytochrome B556 (FDO) subunit (AAD13454.1); Blastp hit to AAD13454.1 (211 aa), 96% identity in aa 1 - 211.
     
  0.900
fdoH
Formate dehydrogenase-O, Fe-S subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
     
  0.900
fdoG
Similar to E. coli formate dehydrogenase-O, major subunit (AAD13456.1); Blastp hit to AAD13456.1 (1016 aa), 93% identity in aa 1 - 1016.
     
  0.900
yohL
Putative cytoplasmic protein; Repressor of rcnA expression. Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt. In the presence of one of these metals, it has a weaker affinity for rcnA promoter (By similarity); Belongs to the FrmR/RcnR family.
  
  
 0.865
STM1628
Putative cytoplasmic protein; Similar to E. coli putative alpha helix chain (AAC73460.1); Blastp hit to AAC73460.1 (98 aa), 52% identity in aa 8 - 98.
  
  
 0.777
yeaL
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74859.1); Blastp hit to AAC74859.1 (148 aa), 94% identity in aa 1 - 130.
     
 0.776
ybeU
Putative cytoplasmic protein; Similar to E. coli putative tRNA ligase (AAC73749.1); Blastp hit to AAC73749.1 (235 aa), 61% identity in aa 1 - 235.
     
 0.752
yacH
Similar to E. coli putative membrane protein (AAC73228.1); Blastp hit to AAC73228.1 (617 aa), 29% identity in aa 3 - 523.
      
 0.723
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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