Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
sprPutative lipoprotein; Suppresses thermosensitivity of prc mutants at low osmolality; similar to E. coli putative lipoprotein (AAC75236.1); Blastp hit to AAC75236.1 (188 aa), 92% identity in aa 1 - 188. (190 aa)    
Predicted Functional Partners:
sprT
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75981.1); Blastp hit to AAC75981.1 (165 aa), 90% identity in aa 1 - 164; Belongs to the SprT family.
      
 0.857
prc
Carboxy-terminal protease for penicillin-binding protein 3; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses (By similarity).
   
 
 0.844
nlpI
Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity).
    
 
 0.799
yeiU
Putative permease; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family.
    0.708
yebA
Putative peptidase; Similar to E. coli orf, hypothetical protein (AAC74926.1); Blastp hit to AAC74926.1 (419 aa), 91% identity in aa 1 - 419.
 
  
 0.696
ydgM
Putative alternative beta subunit of Na+-transporting NADH:ubiquinone oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
   
  
 0.674
rtn
Putative membrane protein involved in resistance to lambda and N4 phages; Similar to E. coli orf, hypothetical protein (AAC75237.1); Blastp hit to AAC75237.1 (518 aa), 70% identity in aa 1 - 518.
 
    0.673
yejA
Putative ABC transporter periplasmic binding protein; Similar to E. coli orf, hypothetical protein (AAC75238.1); Blastp hit to AAC75238.1 (606 aa), 86% identity in aa 3 - 603.
 
    0.644
gldA
Similar to E. coli glycerol dehydrogenase, (NAD) (AAC76927.1); Blastp hit to AAC76927.1 (380 aa), 91% identity in aa 14 - 380.
      
 0.616
yeiP
Similar to E. coli putative elongation factor (AAC75232.1); Blastp hit to AAC75232.1 (275 aa), 83% identity in aa 8 - 275.
    0.598
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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