Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yejHSimilar to E. coli putative ATP-dependent helicase (AAC75245.1); Blastp hit to AAC75245.1 (586 aa), 95% identity in aa 1 - 586. (586 aa)    
Predicted Functional Partners:
yejK
Nucleotide associated protein; Present in spermidine nucleoids; similar to E. coli orf, hypothetical protein (AAC75247.1); Blastp hit to AAC75247.1 (335 aa), 96% identity in aa 1 - 334.
  
   
 0.963
lysP
Similar to E. coli lysine-specific permease (AAC75217.1); Blastp hit to AAC75217.1 (489 aa), 94% identity in aa 1 - 489.
      
 0.719
rplY
50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.
      0.717
rpoB
RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.693
rpoA
RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.690
hepA
RNA polymerase associated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
 
 
 0.617
rpoZ
RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
    
 0.615
dinG
LexA regulated (SOS) repair enzyme; DNA-dependent ATPase and 5'-3' DNA helicase.
   
 0.605
yoaA
Putative DNA helicase; Similar to E. coli putative enzyme (AAC74878.1); Blastp hit to AAC74878.1 (636 aa), 95% identity in aa 1 - 635.
   
 0.605
rsuA
16S rRNA pseudouridylate 516 synthase; Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.
       0.586
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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