Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STM2230Putative peptidase; Similar to E. coli SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC (AAC74267.1); Blastp hit to AAC74267.1 (139 aa), 38% identity in aa 22 - 139; Belongs to the peptidase S24 family. (167 aa)    
Predicted Functional Partners:
umuC
Error-prone repair protein; Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template.
 
 
 0.987
STM2231
ssrB-regulated factor; Similar to msgA; virulence protein msga (SW:MSGA_SALTY).
  
  
 0.956
STM4489
Putative superfamily I DNA helicases; Similar to E. coli putative frameshift suppressor (AAC77264.1); Blastp hit to AAC77264.1 (338 aa), 68% identity in aa 1 - 338.
  
  
 0.952
STM2245
Putative outer membrane protein.
      
 0.941
STM4198
Putative cytoplasmic protein.
   
  
 0.924
STM2237
Putative inner membrane protein.
   
  
 0.923
recA
DNA strand exchange and recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
  
 
 0.921
STM2589
Gifsy-1 prophage protein; Similar to host specificity protein-J in phage lambda.
   
  
 0.897
STM2732
Fels-2 prophage protein; Similar to protein in phage 186.
      
 0.897
STM2240
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74633.1); Blastp hit to AAC74633.1 (362 aa), 84% identity in aa 251 - 362, 43% identity in aa 14 - 238.
      
 0.896
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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