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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
napDPeriplasmic nitrate reductase; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export. (87 aa)    
Predicted Functional Partners:
napA
Periplasmic large subunit nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
  
 
 0.999
napB
Periplasmic small subunit nitrate reductase of cytochrome C550; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.
  
  
 0.994
napH
Ferredoxin-type protein; Electron transfer; similar to E. coli ferredoxin-type protein: electron transfer (AAC75264.1); Blastp hit to AAC75264.1 (287 aa), 88% identity in aa 1 - 280.
  
  
 0.991
napG
Ferredoxin-type protein; Electron transfer; similar to E. coli ferredoxin-type protein: electron transfer (AAC75265.1); Blastp hit to AAC75265.1 (231 aa), 94% identity in aa 1 - 231.
  
  
 0.969
napF
Ferredoxin-type protein; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.
  
  
 0.942
napC
Periplasmic nitrate reductase; Cytochrome c-type biogenesis protein; similar to E. coli cytochrome c-type protein (AAC75262.1); Blastp hit to AAC75262.1 (200 aa), 88% identity in aa 1 - 200.
  
  
 0.925
STM2527
Putative polyferredoxin; Similar to E. coli hydrogenase 4 Fe-S subunit (AAC75541.1); Blastp hit to AAC75541.1 (181 aa), 36% identity in aa 33 - 124, 40% identity in aa 42 - 90.
  
  
 0.914
STM0610
Putative component of anaerobic dehydrogenases; Similar to E. coli putative oxidoreductase component (AAC74663.1); Blastp hit to AAC74663.1 (207 aa), 30% identity in aa 78 - 196.
      
 0.896
fdnG
Putative molybdopterin oxidoreductases; Similar to E. coli formate dehydrogenase-N, nitrate-inducible, alpha subunit (AAD13438.1); Blastp hit to AAD13438.1 (1015 aa), 93% identity in aa 1 - 1015; contains selenocysteine tRNA suppressible codon.
  
 
 0.840
fdoG
Similar to E. coli formate dehydrogenase-O, major subunit (AAD13456.1); Blastp hit to AAD13456.1 (1016 aa), 93% identity in aa 1 - 1016.
  
 
 0.840
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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