Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ecoEcotin; General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. (164 aa)    
Predicted Functional Partners:
ycfF
Putative protein kinase C inhibitor; Similar to E. coli orf, hypothetical protein (AAC74187.1); Blastp hit to AAC74187.1 (119 aa), 97% identity in aa 1 - 119.
      
 0.528
STM2532
Putative inner membrane lipoprotein; Protects the bacterial cell from host peptidases.
  
   
 0.485
ybeS
Putative molecular chaperone, DnaJ family; Similar to E. coli putative enzyme of polynucleotide modification (AAC73747.1); Blastp hit to AAC73747.1 (475 aa), 45% identity in aa 1 - 474.
  
     0.466
allR
Putative regulatory protein; Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS-allA intergenic region (By similarity).
      
 0.451
yebF
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74917.1); Blastp hit to AAC74917.1 (122 aa), 76% identity in aa 5 - 122.
      
 0.450
yhjL
Putative TPR-repeat-containing protein; Required for maximal bacterial cellulose synthesis. Belongs to the AcsC/BcsC family.
  
     0.447
ybeV
Putative molecular chaperone, DnaJ family; Similar to E. coli orf, hypothetical protein (AAC73750.1); Blastp hit to AAC73750.1 (483 aa), 58% identity in aa 1 - 434.
  
     0.435
nrfB
Formate-dependent nitrite reductase; A penta-haeme cytochrome c; similar to E. coli formate-dependent nitrite reductase; a penta-haeme cytochrome c (AAC77041.1); Blastp hit to AAC77041.1 (190 aa), 88% identity in aa 1 - 190.
  
   
 0.427
nrfG
Involved in attachment of haem c to cytochrome c552; similar to E. coli part of formate-dependent nitrite reductase complex (AAD13459.1); Blastp hit to AAD13459.1 (198 aa), 71% identity in aa 6 - 196.
  
     0.418
stdB
Similar to E. coli putative membrane protein (AAC76082.1); Blastp hit to AAC76082.1 (821 aa), 42% identity in aa 20 - 817.
  
     0.416
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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