Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ubiG3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (242 aa)    
Predicted Functional Partners:
ubiF
Putative monooxygenase; Similar to E. coli orf, hypothetical protein (AAC73763.1); Blastp hit to AAC73763.1 (391 aa), 85% identity in aa 1 - 391.
 
 0.997
ubiH
2-octaprenyl-6-methoxyphynol hydroxylase; Similar to E. coli 2-octaprenyl-6-methoxyphenol--> 2-octaprenyl-6-methoxy-1, 4-benzoquinone (AAC75945.1); Blastp hit to AAC75945.1 (392 aa), 79% identity in aa 1 - 392.
 
 0.997
visC
Putative monooxygenase; Similar to E. coli orf, hypothetical protein (AAC75944.1); Blastp hit to AAC75944.1 (400 aa), 87% identity in aa 1 - 400.
 
 0.983
ubiA
P-hydroxybenzoate: octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
 
 
 0.982
ubiE
S-adenosylmethionine; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
 
 
 0.973
yhbT
Putative lipid carrier protein; Similar to E. coli orf, hypothetical protein (AAC76191.1); Blastp hit to AAC76191.1 (174 aa), 90% identity in aa 1 - 174.
  
 
 0.920
yhbV
Putative protease; Similar to E. coli orf, hypothetical protein (AAC76193.1); Blastp hit to AAC76193.1 (298 aa), 91% identity in aa 1 - 298.
    
 0.912
yhbU
Similar to E. coli putative collagenase (AAC76192.1); Blastp hit to AAC76192.1 (331 aa), 96% identity in aa 1 - 331.
    
 0.906
yigC-2
Putative oxidoreductase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
      
 0.793
STM2275
Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74613.1); Blastp hit to AAC74613.1 (228 aa), 25% identity in aa 13 - 217.
       0.773
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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