Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
glpTMFS family, sn-glycerol-3-phosphate transport protein; Similar to E. coli sn-glycerol-3-phosphate permease (AAC75300.1); Blastp hit to AAC75300.1 (452 aa), 96% identity in aa 1 - 452. (452 aa)    
Predicted Functional Partners:
glpQ
Similar to E. coli glycerophosphodiester phosphodiesterase, periplasmic (AAC75299.1); Blastp hit to AAC75299.1 (358 aa), 89% identity in aa 1 - 357.
 
  
 0.999
glpF
Similar to E. coli facilitated diffusion of glycerol (AAC76909.1); Blastp hit to AAC76909.1 (281 aa), 92% identity in aa 1 - 281; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
  
 0.983
glpA
Similar to E. coli sn-glycerol-3-phosphate dehydrogenase (anaerobic), large subunit (AAC75301.1); Blastp hit to AAC75301.1 (542 aa), 92% identity in aa 1 - 542; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.962
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
  
  
 0.952
glpB
Sn-glycerol-3-phosphate dehydrogenase (anaerobic), membrane anchor subunit; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor; Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
 
  
 0.934
glpC
Similar to E. coli sn-glycerol-3-phosphate dehydrogenase (anaerobic), K-small subunit (AAC75303.1); Blastp hit to AAC75303.1 (396 aa), 94% identity in aa 1 - 395.
 
  
 0.907
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
      
 0.907
pitA
PiT family; similar to E. coli low-affinity phosphate transport (AAC76518.1); Blastp hit to AAC76518.1 (499 aa), 92% identity in aa 1 - 499.
      
 0.860
glpD
Aerobic; similar to E. coli sn-glycerol-3-phosphate dehydrogenase (aerobic) (AAC76451.1); Blastp hit to AAC76451.1 (501 aa), 90% identity in aa 1 - 501; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.816
uhpA
Response regulator (repressor) in two-component regulatory system wtih UhpB; Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. Activates the transcription of the uhpT gene. Acts by binding specifically to the uhpT promoter region.
      
 0.767
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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