Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yfbQPutative regulator; similar to E. coli putative aminotransferase (AAC75350.1); Blastp hit to AAC75350.1 (405 aa), 96% identity in aa 1 - 404. (404 aa)    
Predicted Functional Partners:
aspC
Similar to E. coli aspartate aminotransferase (AAC74014.1); Blastp hit to AAC74014.1 (396 aa), 95% identity in aa 1 - 396; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
   
 0.959
nifJ
Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174.
  
 
 0.925
avtA
Valine-pyruvate aminotransferase; Similar to E. coli alanine-alpha-ketoisovalerate (or valine-pyruvate) transaminase, transaminase C (AAC76596.1); Blastp hit to AAC76596.1 (417 aa), 92% identity in aa 1 - 415.
   
 
 0.925
pheA
Chorismate mutase P; Bifuctional; similar to E. coli chorismate mutase-P and prephenate dehydratase (AAC75648.1); Blastp hit to AAC75648.1 (386 aa), 90% identity in aa 1 - 385.
 
 0.923
ilvE
Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine.
  
 
 0.919
argA
N-alpha-acetylglutamate synthase; Amino-acid acetyltransferase; similar to E. coli N-acetylglutamate synthase; amino acid acetyltransferase (AAC75857.1); Blastp hit to AAC75857.1 (443 aa), 93% identity in aa 1 - 443; Belongs to the acetyltransferase family. ArgA subfamily.
  
 
 0.915
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.912
STM3531
Similar to E. coli putative dehydratase (AAC73372.1); Blastp hit to AAC73372.1 (655 aa), 39% identity in aa 86 - 578; Belongs to the IlvD/Edd family.
   
 
 0.910
ilvD
Dihydroxy-acid dehydratase. (SW:ILVD_SALTY); Belongs to the IlvD/Edd family.
   
 
 0.910
gdhA
NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
  
 
 0.907
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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